Important Note: Redirection of Services to ChiCTR
We would like to inform you that the Clinical Trial Registry page will discontinue the function of updating trial information directly on this platform. However, you will still be able to view the existing registration details. For any updates to trial information, you can use the China Clinical Trial Registry (ChiCTR) directly at https://www.chictr.org.cn. This change will be fully implemented by 2024-Aug-05. Thank you for your attention.
CUHK_CCRB00590
2018-03-08
Prospective
2017.609-T
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
Department of Medicine, The Chinese University of Hong Kong
Not Applicable
Mr Freddie Chiu
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
35052735
freddie@cuhk.edu.hk
The Chinese University of Hong Kong
Hong Kong
Teresa Hing Yan Tsang
Department of Anaesthesia and Intensive Care, Prince of Wales Hospital
98069139
teresahytsang@gmail.com
Department of Anaesthesia and Intensive Care, Prince of Wales Hospital
Hong Kong
Beneficial effects of high flow nasal cannula (HFNC) versus standard low flow nasal cannula in patients undergoing left atrial appendage occlusion (LAAO) under deep sedation: A randomized pilot crossover trial
Beneficial effects of high flow nasal cannula (HFNC) versus standard low flow nasal cannula in patients undergoing left atrial appendage occlusion (LAAO) under deep sedation: A randomized pilot crossover trial
高流量鼻插管（HFNC）與標準低流量鼻插管在深度監察麻醉下進行左心耳閉塞(LAAO)患者的有益效果
Use of high flow nasal cannula (HFNC) in patients undergoing left atrial appendage occlusion (LAAO) under deep sedation
Hong Kong
Yes
2018-01-31
Joint CUHK-NTEC Clinical Research Ethics Committee
2017.609-T
left atrial appendage occlusion (LAAO)
Device
high flow nasal cannula (HFNC) Optiflow THRIVE
Inhalation
50 litres min-1
30 minutes
Not Applicable
standard low flow nasal cannula
Inhalation
4 litres min-1
30 minutes
Not Applicable
Subjects undergoing left atrial appendage occlusion with deep sedation in the cardiac intervention laboratory
Subjects who are unable to tolerate the high flow nasal cannula secondary to discomfort
Subjects who are with aspiration risks and will require endotracheal intubation
Severe obstructive sleep apnoea
Subjects with anticipated difficult airway
Subjects with chronic carbon dioxide retention
18
100
Both Male and Female
Interventional
Randomized
All patients are assigned randomly to the 2 sequence groups
Active
Open label
Crossover
Other
Not Applicable
2018-03-12
30
Not Yet Recruiting
Frequency of desaturation episodes
Oxygen saturation less than 92% for greater than 15 seconds at any point during the patient's anaesthesia
Rate of change of arterial blood gases, including partial pressure of oxygen (PaO2), partial pressure of carbon dioxide and pH over time
Blood gases will be sampled at 10 minutes intervals.
Need for airway manipulation
The need for manipulation of the airway by the anaesthesiologist in the event of upper airway obstruction (combined numbers of episode for jaw thrust, repositioning of the patient’s head, tactile stimulation) to maintain a patent airway and adequate oxygenation with SpO2 > 92 %
Respiratory rate
The rate of respiration of the patient under sedation as measured by capnography or thoracic impedance
Tolerability
Procedure interruption due to patient’s intolerance
Postoperative outcome in the recovery unit
Arterial blood gas (PaO2, PaCO2, pH) characteristics in the recovery unit upon admission and discharge; episodes of desaturation episodes < 92 %
2020-03-06
ChiCTR1800015146
2018-03-08
|
|
|
|
|
|
|---|---|---|---|---|
| No documents yet. | ||||